- Turkish Journal of Clinics and Laboratory
- Vol: 14 Issue: 2
- FACTORS AFFECTING ADEQUATE MYOCARDIAL PERFUSION IN PATIENTS WITH ACUTE ST-ELEVATION MYOCARDIAL INFAR...
FACTORS AFFECTING ADEQUATE MYOCARDIAL PERFUSION IN PATIENTS WITH ACUTE ST-ELEVATION MYOCARDIAL INFARCTION WITH SUCCESSFUL EPICARDIAL FLOW
Authors : Faruk AYDINYILMAZ, Nail Burak ÖZBEYAZ, Engin ALGUL, İlkin GULIYEV, Haluk Furkan ŞAHAN, Ayşenur ÖZKAYA İBİŞ, Kamuran KALKAN, Hamza SUNMAN
Pages : 228-236
Doi:10.18663/tjcl.1205470
View : 20 | Download : 16
Publication Date : 2023-06-30
Article Type : Research Article
Abstract :Aim: The aim of this study was to evaluate and compare multifarious parameters between complete and incomplete ST-segment resolution (STR) patients groups and to identify associates of STR in patients with acute ST-segment elevation myocardial infarction (STEMI) after successful primary percutaneous coronary intervention (pPCI). Material and Methods: 888 consecutive patients were divided into two groups according to the STR <70% and ≥70% 60-90 min after pPCI. The cardiovascular risk factors and various angiographic parameters were assessed and compared between the groups. Results: There were 346 patients with incomplete STR and 542 patients with complete STR. In multivariable regression analysis, culprit lesion (LAD) (OR=1.768; p=0.048), door-to-wire crossing time (OR=0.993; p=0.033), total procedure time (OR=0.994; p=<0.001) and glycoprotein 2b/3a inhibitor use (OR=2.135; p=0.013) were found to be independent risk factors for complete STR. The AUC of door-to-wiring and total procedure time for STR prediction was 0.668, 0.831, the cut-off value was 58, 52 min, and the sensitivity and specificity were 63.9%, 70.8%, and 63.1%, 76.8%. Conclusion: Even if the successful flow is achieved at the end of pPCI, keeping the procedure time as short as possible and using glycoprotein 2b/3a are the factors that can increase perfusion at the myocyte level.Keywords : ST elevasyonlu miyokard enfarktüsü, TIMI-3 akım, ST elevasyon rezolüsyonu, elektrokardiyografi