- Turkish Journal of Veterinary and Animal Sciences
- Vol: 23 Issue: 5
- Role of Vitamin E in Decreasing the Toxic Effect of Digoxin
Role of Vitamin E in Decreasing the Toxic Effect of Digoxin
Authors : Ismail Meral, Burhanettin Baydaş, Fahri Bayiroğlu
Pages : 445-450
View : 5 | Download : 3
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :This experiment was carried out to evaluate the role of vitamin E in decreasing the toxic effect of digoxin. Electrocardiographic recordings of New Zealand rabbits which were treated with digoxin-only or digoxin+vitamin E were used. Recordings were obtained before and 24 hours after treatments. It was found that digoxin-only treatment caused a sinusoidal tachicardia without changing the durations or amplitudes of any wave on the trace. However, digoxin+vitamin E treatment did not produce any increase in heart rate. It was concluded that vitamin E injection along with digoxin injection might lower the toxic effect of digoxin. More studies are needed to convince these findings.Keywords : Digoxin, Vitamin E, Rabbits, Electrocardiogram.