- Turkish Journal of Medical Sciences
- Vol: 50 Issue: 4
- Evaluation of the cardioprotective effects of crystalloid del Nido cardioplegia solution via a rapid...
Evaluation of the cardioprotective effects of crystalloid del Nido cardioplegia solution via a rapid and accurate cardiac marker: heart-type fatty acid-binding protein
Authors : Mehmet Kirişci, Aydemir Koçarslan, Duygun Altintaş Aykan, Filiz Alkan Baylan, Adem Doğaner, Yavuz Orak
Pages : 999-1006
Doi:10.3906/sag-2002-53
View : 13 | Download : 0
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :Background/aim: Our aim in this study was to compare the efficacy and safety of crystalloid del Nido solution and cold blood cardioplegia solution on clinical and laboratory parameters. Materials and methods: Sixty patients who underwent elective coronary bypass operation between July 2019 and January 2020 were included in our study. Patients were divided into 2 groups of 30 patients using del Nido solution DNS and cold blood cardioplegia solution CBCS , which were given for cardiac arrest. Demographic data, preoperative, postoperative 0th h, 6th h and 4th day creatine kinase myocardial band CK-MB and troponin I values were compared with a specific cardiac enzyme heart-type fatty acid-binding protein H-FABP . Results: We found that aortic cross clamp duration and cardiopulmonary bypass CPB time were shorter in patients using del Nido solution than cold blood cardioplegia solution 57.30 ± 23.57 min, 76.07 ± 27.18 min, P = 0.006 95.07 ± 23.06 min, 114.13 ± 33.93, P = 0.014 . Total cardioplegia solution volume was higher in the cold blood cardioplegia solution group 1426.67 ± 416.00 vs. 1200 ± 310.73 P = 0.02 . Preoperative and postoperative levels of cardiac enzymes including CK-MB, troponin I and H-FABP were comparable in del Nido solution and cold blood cardioplegia solution groups. Conclusion: According to these results, when we compare both demographic data and CK-MB, troponin I and H-FABP levels, both cardioplegia solutions were comparable regarding safety and efficacy in terms of myocardial protection.Keywords : Heart-type fatty acid-binding protein, cold blood cardioplegia solution, del Nido solution, coroner artery bypass grafting, myocardial protection