- Turkish Journal of Medical Sciences
- Vol: 50 Issue: 2
- Prognostic role of homeostasis model assessment and oral glucose tolerance test in nondiabetic patie...
Prognostic role of homeostasis model assessment and oral glucose tolerance test in nondiabetic patients with Bell's palsy
Authors : Tuğba Karagöz, Ömer Bayir, Emel Çadallı Tatar, Erman Çakal, Ali Özdek, Kemal Keseroğlu, Mustafa Şahin, Mehmet Hakan Korkmaz
Pages : 405-410
Doi:10.3906/sag-1901-151
View : 15 | Download : 3
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :Background/aim: We aimed to reveal the incidence and predictive role of insulin resistance and distorted oral glucose tolerance test in nondiabetic patients with Bell's Palsy BP . Materials and methods: Eighty-six patients with BP and 28 control subjects; all with normal blood glucose levels and no history of diabetes, were enrolled in the study. We investigated insulin resistance IR in all subjects, in terms of HOMA-IR greater than 2.7. Sixtytwo of the patients also underwent an oral glucose tolerance test OGTT . Results: The mean HOMA-IR value was significantly increased in patients, compared to the control group 3.2 vs 1.6; P < 0.01 . IR was detected more in BP patients than in controls P < 0.05 . The patients with higher HOMA-IR values had more severe facial dysfunction at the initial presentation and complete recovery time took longer than the patients with normal HOMA-IR value 75 days vs 42 days; P < 0.05 . Following a 2h-OGTT, impaired glucose tolerance and newly diagnosed DM were found in 60% of the patients. Recovery time was significantly longer in prediabetics and newly diagnosed diabetic patients than in patients with normal glycemia 68 days, 52 days, and 32 days, respectively; P < 0.01 . Conclusion: There is a strong linkage between HOMA-IR value and BP prognosis so HOMA-IR value may have a significant role of predicting BP prognosis at presentation.Keywords : Bell's palsy, insulin resistance, prediabetes, HOMA-IR index