- Turkish Journal of Medical Sciences
- Vol: 49 Issue: 3
- Contribution of DECT in detecting serosal invasion of gastric cancer
Contribution of DECT in detecting serosal invasion of gastric cancer
Authors : Ali KÜPELİ, Eser BULUT, Ayşegül CANSU, Ali GÜNER, Mehmet SOYTÜRK, Gürkan DANIŞAN
Pages : 782-788
View : 13 | Download : 2
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :Background/aim: This study aimed to investigate the relationship between the iodine concentration (IC) of perigastric fat tissue as assessed by dual-energy computed tomography (DECT) and serosal invasion of gastric cancer.Materials and methods: A total of 41 patients underwent preoperative staging evaluation for gastric cancer using DECT between July 2015 and March 2018. Patients were divided into 2 groups based on pathology results: serosal invasion (stage T4a) and intact serosa (stages T1-T3). Cutoff values, the diagnostic efficacy of IC in the perigastric fat tissue, and the perigastric fat tissue/tumor (P/T) ratio were determined.Results: Among the 41 patients, 22 had stage T4a gastric cancer and 19 patients had gastric cancer with a stage lower than T4a. The mean IC of perigastric fat tissue and the P/T ratio were significantly higher in patients with serosal invasion than in those with intact serosa (P < 0.001). During the arterial phase, the area under the curve (AUC) was 0.915 and 0.854 for the IC of perigastric fat tissue and the P/T ratio, respectively. During the venous phase, the AUC was 0.890 and 0.876 for the IC of perigastric fat tissue and the P/T ratio, respectively.Conclusion: The IC in the perigastric fat tissue seems to be a reliable indicator for serosal invasion of gastric cancer.Keywords : DECT, gastric cancer, iodine concentration