- Turkish Journal of Medical Sciences
- Vol: 48 Issue: 4
- Rising stars of DPLD survival: FVC and exercise desaturation (a single-center study)
Rising stars of DPLD survival: FVC and exercise desaturation (a single-center study)
Authors : Ayperi Öztürk, Oya Kayacan
Pages : 826-832
View : 9 | Download : 2
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :Background/aim: Diffuse parenchymal lung diseases (DPLDs) comprise a broad, heterogeneous group of diseases with common functional characteristics and a common final pathway, usually leading to irreversible fibrosis. We investigated the effects of the physiological and functional parameters and of pulmonary hypertension (PH) on survival in DPLDs. Materials and methods: The study included 158 patients with DPLDs. Patient data were examined retrospectively, and survival status was obtained through phone calls. Results: Patients were divided into five groups according to their diagnosis: idiopathic pulmonary fibrosis (IPF), non-IPF idiopathic interstitial pneumonias, connective tissue diseases, sarcoidosis, and other DPLDs. Median survival was 42.9 months. The significant negative effects of older age, presence of delta saturation (DeltaSat; difference between oxygen saturation at rest and after the 6-min walking test), 6-min walking distance (Keywords : Desaturation, diffuse parenchymal lung diseases, forced vital capacity, survival, pulmonary hypertension