- Turkish Journal of Medical Sciences
- Vol: 46 Issue: 4
- N-terminal-pro brain natriuretic peptide levels in children with allergic rhinitis
N-terminal-pro brain natriuretic peptide levels in children with allergic rhinitis
Authors : Hasibe Artaç, Hüsamettin Vatansev, Derya Çimen, Derya Arslan, Fatma Kaya, Seyit Ali Kayiş, Bülent Oran
Pages : 1130-1134
View : 13 | Download : 3
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :Background/aim: Persistent upper airway obstruction may lead to increased pulmonary arterial pressure (PAP). The aim of this study was to evaluate N-terminal pro brain natriuretic peptide (NT-proBNP) concentrations and PAP values in children with allergic rhinitis. Materials and methods: Sixty-six patients with allergic rhinitis and 22 healthy children were prospectively enrolled in this study. Plasma NT-proBNP levels were measured at first admission and after treatment. Simultaneously, echocardiography was done to assess pulmonary arterial hypertension, and rhinitis symptom scores were recorded. Results: The median age of the study group was 9.0 (5.0?17.0) years; 26 were female. PAP was found to be normal in all the patients. There was a negative correlation between age and NT-proBNP levels (r = ?0.452, P < 0.01). Nasal blockage levels affected NT-proBNP levels mildly (P = 0.067). No significant difference between before and after nasal steroid treatment was observed in NT-proBNP levels. Conclusion: These results suggest that NT-proBNP level and PAP may not be affected in children with allergic rhinitis, and primarily this influence may be associated with the severity of nasal obstruction.Keywords : Allergic rhinitis, pulmonary arterial pressure, N-terminal pro B-type natriuretic peptide, nasal obstruction, cardiac evaluation