- Turkish Journal of Medical Sciences
- Vol: 45 Issue: 4
- Cardiac factors affecting the success of vardenafil in erectile dysfunction
Cardiac factors affecting the success of vardenafil in erectile dysfunction
Authors : Kürşad Zengin, Hüseyin Ede, Serhat Tanik, Sebahattin Albayrak, Savaş Sarikaya, Aliriza Erbay, Muhammet Abdurrahim Imamoğlu, Mesut Gürdal
Pages : 751-757
Doi:10.3906/sag-1407-69
View : 16 | Download : 4
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :Background/aim: To evaluate the predictability of vardenafil success in patients with erectile dysfunction (ED) by using cardiological tests. Materials and methods: Patients diagnosed with ED who did not benefit from lifestyle changes (n = 68) were evaluated with an abridged 5-item version of the International Index of Erectile Function (IIEF-5). The pretreatment and posttreatment IIEF-5 scores were compared with pretreatment data obtained from cardiological examinations. Results: When pretreatment scores were compared with test parameters, mitral flow E/A ratio and tissue Doppler imaging (TDI) E?/A?, exercise test duration, exercise capacity in MET, and percentage of maximum heart rate were found to be statistically significant. Furthermore, there was a significant negative correlation between mitral flow E/A ratio, TDI E?/A?, exercise test duration, exercise capacity in MET, and the difference in post- and pretreatment IIEF-5 scores. Conclusion: As a diastolic function indicator, TDI E?/A? positively correlates with pretreatment IIEF-5 scores and negatively correlates with the beneficial effect of vardenafil treatment. As a result, the cardiological status of the patient correlates with individual IIEF-5 scores, and it seems to be useful in predicting vardenafil success.Keywords : Erectile dysfunction, phosphodiesterase type 5 inhibitor, diastolic dysfunction