- Turkish Journal of Medical Sciences
- Vol: 45 Issue: 1
- An alternative marker of low-density lipoprotein cholesterol in coronary artery disease: non-high-de...
An alternative marker of low-density lipoprotein cholesterol in coronary artery disease: non-high-density lipoprotein cholesterol
Authors : Müjgan Ercan, Esra Oğuz, Fatma Meriç Yilmaz, Nihal Boğdaycioğlu, Kübranur Ünal, Deniz Şahin, Sema Uysal
Pages : 153-158
Doi:10.3906/sag-1308-116
View : 15 | Download : 3
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :Dyslipidemia is one of the most important risk factors for coronary artery disease (CAD), and low-density lipoprotein cholesterol (LDL-C) is used to measure dyslipidemia. Non-high-density lipoprotein cholesterol (non-HDL-C) seems to be an alternative parameter to LDL-C as it is not influenced by triglyceride (TG) levels. The aim of this study is to compare non-HDL-C and LDL-C levels as risk markers in CAD patients. Materials and methods: One hundred and ten CAD patients and 42 individuals with normal coronary angiography results were included in this study. Patients were divided into 2 groups: TG < 200 mg/dL (n = 75) as group 1 and TG > 200 mg/dL (n = 35) as group 2. Total cholesterol (TC), TG, and HDL-C levels were analyzed with a Roche Modular P800 autoanalyzer. LDL-C and non-HDL-C levels were calculated. Results: There were statistically significant differences in TC, TG, HDL-C, and non-HDL-C levels when the groups were compared. Non-HDL-C levels of group 2 were statistically higher than those of group 1 and the control group. There was no significant difference in LDL-C levels between the groups. Conclusion: Non-HDL-C levels are better risk markers than LDL-C levels, especially in patients with TG > 200 mg/dL, and non-HDL-C levels should be taken into consideration when evaluating the risk of CAD.Keywords : Non-high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, coronary artery disease