- Turkish Journal of Medical Sciences
- Vol: 28 Issue: 3
- Red Cell Membrane Protein Abnormalities of A Family with Hereditary Spherocytosis in Adana
Red Cell Membrane Protein Abnormalities of A Family with Hereditary Spherocytosis in Adana
Authors : Serap Yalin
Pages : 295-298
View : 9 | Download : 8
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :To investigate erythrocyte membrane protein abnormalities in Çukurova region we studied a family observed to be hereditary spherocytosis. Diagnosis was made basis of clinical features. By densitometric tracing of SDS-PAGE stained by Coomassie Brillant Blue, we found two spectrin deficiency, one ankyrin deficeiency, two spectrin-band 3 deficiency, one ankyrin-band 3 deficiency and one combined spectrin-ankyrin- band 3 deficiency.Keywords : Hereditary Spherocytosis, Spectrin, Ankyrin, Band 3, Red Cell Membrane.