- Turkish Journal of Medical Sciences
- Vol: 29 Issue: 6
- The Effects of Flutamide on Lipid Profile, Insulin Sensitivity, Hirsutism and Gonadotropins in Women...
The Effects of Flutamide on Lipid Profile, Insulin Sensitivity, Hirsutism and Gonadotropins in Women With Polycystic Ovary Syndrome
Authors : Mithat Bahçeci
Pages : 677-682
View : 7 | Download : 4
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :In this study, we evaluated metabolic changes and the effects of flutamide in 22 women with PCOS. Flutamide was administered for a 6-month period in a dose of 750 mg/day. The basal and after treatment body mass index, waist: hip ratio, blood glucose, insulin, lipids, Ferriman-Gallwey scoring (FGS), gonadotropins, testosterone, trasaminazed and glucose: insulin (G:I) ratio were measured. For comparison, ANOVA was used. The sixth month mean FGS was significantly lower than the basal values (18.5±7.4 and 12.5±4.5, PKeywords : insulin sensitivity, PCOS, flutamide, hirsutism and lipids.