- Turkish Journal of Medical Sciences
- Vol: 34 Issue: 6
- Chromosomal Aberrations in Radiation Waste Repository Workers Detected by Fish Painting and Giemsa S...
Chromosomal Aberrations in Radiation Waste Repository Workers Detected by Fish Painting and Giemsa Staining
Authors : Petia Atanasova, Valeria Hadjidekova, Savina Agova
Pages : 359-365
View : 9 | Download : 6
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :We aimed to assess chromosomal aberration frequency by means of FISH chromosome painting and conventional Giemsa staining in peripheral blood lymphocytes of workers at a nuclear waste repository. The results obtained from the exposed group were compared with those from a control group from the administrative staff of the company. Data on health and social status were collected using a questionnaire. Conventional chromosomal analysis after Giemsa staining did not indicate any significant difference between radiation exposed and control workers. Analysis after FISH chromosome painting revealed a 2-fold increased in genomic frequency of stable chromosomal translocations in the exposed group over the control group. The difference is of marginal statistical significance.Keywords : Occupational radiation exposure, Human lymphocytes, Chromosomal aberrations, Fluorescent in situ hybridization