- Turkish Journal of Medical Sciences
- Vol: 35 Issue: 2
- In Vitro Testing for Genotoxicity of 4-CPA by Sister Chromatid Exchange in Human Lymphocyte Culture
In Vitro Testing for Genotoxicity of 4-CPA by Sister Chromatid Exchange in Human Lymphocyte Culture
Authors : Hüseyin Bağci, Gülseren Bağci, Ibrahim Açikbaş, Göksemin Demir
Pages : 75-78
View : 19 | Download : 6
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :Certain phenoxyacetate derivatives used as plant growth regulators act as plant hormones. 2,4-D dichlorophenoxyacetic acid and 4-chlorophenoxyacetic acid are widely used in vegetable growing, especially tomatoes, in our region. These phenoxyacetic acid compounds are a potential hazard for the environment. There are conflicting results and inconsistent data about these herbicides in the literature. This is the first report of genotoxicity of 4-CPA evaluated by sister chromatid exchange in human lymphocyte culture. No significant change was found in sister chromatid exchange frequency at the tested 4-CPA concentration.Keywords : 4-CPA, Phenoxy herbicides, genotoxicity, sister chromatid exchange, tomato