- Turkish Journal of Medical Sciences
- Vol: 43 Issue: 5
- Association between maternal ghrelin levels and hyperemesis gravidarum
Association between maternal ghrelin levels and hyperemesis gravidarum
Authors : Ikbal Kaygusuz, Ilknur Inegöl Gümüş, Melahat Yildirim, Hüsamettin Erdamar
Pages : 790-794
Doi:10.3906/sag-1209-9
View : 16 | Download : 6
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :To investigate serum levels of ghrelin in pregnant women as a potential early marker for hyperemesis gravidarum (HG). Materials and methods: A cross-sectional study was carried out at Fatih University Hospital. Included in the study were 35 women with HG and 31 pregnant women without HG as a control group. The groups were compared in terms of age, gravidity, body mass index (BMI), and fasting serum thyroid-stimulating hormone (TSH) and ghrelin levels. Results: Ghrelin levels of the patients with HG were found to be significantly lower than those in the control group (P = 0.03). No intergroup differences could be found in serum TSH or BMI values . Conclusion: Ghrelin might serve as a reliable marker in the etiopathogenesis of HG.Keywords : Key words: Hyperemesis gravidarum, pregnancy, ghrelin, etiopathogenesis, thyroid-stimulating hormone, body mass index