- Turkish Journal of Chemistry
- Vol: 42 Issue: 1
- Facile synthesis of heteroaryl substituted -lactams from nitrovinyl arenes
Facile synthesis of heteroaryl substituted -lactams from nitrovinyl arenes
Authors : Seda ÇINAR, Canan ÜNALEROĞLU
Pages : 29-35
View : 8 | Download : 3
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :Aliphatic nitroalkanes with different functional groups were synthesized from the Michael addition reactions of active methylene compounds 2 and nitrovinyl arenes 1 in high yields. The synthesized Michael adducts were subjected to intramolecular cyclization to give heteroaryl substituted γ-lactams in good to high yields under mild reaction conditions.Keywords : γ-Lactam, aliphatic nitroalkanes, Michael addition, nitrovinyl arenes