- Turkish Journal of Chemistry
- Vol: 41 Issue: 4
- Diastereoselective synthesis of novel 2,5-dioxopyrrolidine derivatives via biocatalytic domino react...
Diastereoselective synthesis of novel 2,5-dioxopyrrolidine derivatives via biocatalytic domino reactions
Authors : Saadieh Mohajer, Robabeh Baharfar
Pages : 502-513
View : 11 | Download : 8
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :A series of novel 2,5-dioxopyrrolidines were synthesized by the one-pot reaction of coumarin-3-carboxylic acids 1 with thiourea derivatives and alkyl isocyanides in the presence of Fe$_{3}$O$_{4}$ NPs @ lipase as heterogeneous reusable nanobiocatalysts with high yields.Keywords : Diastereoselective synthesis, 2, 5-dioxopyrrolidine derivatives, biocatalytic reactions