- Turkish Journal of Chemistry
- Vol: 41 Issue: 1
- Graphite oxide catalyzed synthesis of $\beta $-amino alcohols by ring-opening of epoxides
Graphite oxide catalyzed synthesis of $\beta $-amino alcohols by ring-opening of epoxides
Authors : Maryam Mirza-aghayan, Farzaneh Alvandi, Mahdieh Molaee Tavana, Rabah Boukherroub
Pages : 70-79
View : 6 | Download : 4
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :Graphite oxide as a heterogeneous and recyclable solid acid catalyzed a simple and efficient method for the synthesis of $\beta $-amino alcohols by ring opening of epoxides with amines. This method is effective with various aromatic and aliphatic amines under solvent-free conditions. The corresponding $\beta $-amino alcohols are obtained in high yields (56%-95%) and short reaction times (15-30 min) with high regio- and chemoselectivity under metal-free conditions.Keywords : Ring opening, epoxides, amines, $eta $-amino alcohols, graphite oxide, metal-free conditions