- Turkish Journal of Chemistry
- Vol: 40 Issue: 2
- Synthetic access to some new benzothiazole-based 1,3,4-thiadiazole and 1,3-thiazole derivatives
Synthetic access to some new benzothiazole-based 1,3,4-thiadiazole and 1,3-thiazole derivatives
Authors : Kamal M. Dawood, Eman A. Ragab, Korany A. Ali
Pages : 277-282
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Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :1-(Benzothiazol-2-yl)-3-phenylthiourea\textbf{ 2} was prepared and treated with hydrazonoyl chlorides \textbf{3a}--\textbf{e }to yield the corresponding 5-(benzothiazol-2-ylimino)-1,3,4-thiadiazole derivatives \textbf{6a}--\textbf{e}, respectively. Reaction of the thiourea derivative \textbf{2} with ethyl 2-chloro-3-oxobutanoate \textbf{9} afforded the corresponding 2-(benzothiazol-2-ylimino)thiazole-5-carboxylate derivative \textbf{11}. The newly synthesized heterocyclic derivatives were confirmed from their elemental and spectral analyses.Keywords : Benzothiazole, thiazole, thiadiazole, thiourea, hydrazonoyl chlorides