- Turkish Journal of Chemistry
- Vol: 39 Issue: 6
- Synthesis of new thiol-derivatized aminophosphines and their catalytic activities in C--C coupling r...
Synthesis of new thiol-derivatized aminophosphines and their catalytic activities in C--C coupling reactions
Authors : Nermin Biricik, Nermin Meriç, Cezmi Kayan, Zeynep Özgen, Sevil Şeker Azizoğlu, Bahattin Gümgüm
Pages : 1257-1264
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Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :A series of new aminophosphines [Ph$_{2}$PHN-C$_{6}$H$_{4}$-R, where R = $o$-SH (\textbf{4a}), $m$-SH (\textbf{4b) or }$p$-SH (\textbf{4c})] were readily synthesized from cheap starting materials by the phosphorylation reaction of $o$, $m$, and $p$-aminothiophenols with Ph$_{2}$PCl in the presence of triethyl amine. The new compounds were characterized by NMR and IR spectroscopy and microanalysis. In addition, aminophosphine ligands--palladium systems were investigated as precatalysts in C--C coupling reactions. Compounds \textbf{4b} and \textbf{4c }were proved to be excellent catalysts for Suzuki and Heck cross-coupling reactions.Keywords : Aminophosphine, synthesis, catalysis, palladium, Suzuki--Heck