- Turkish Journal of Chemistry
- Vol: 39 Issue: 6
- Palladium-catalyzed ligand-free and efficient Suzuki--Miyaura reaction of $N$-methyliminodiacetic ac...
Palladium-catalyzed ligand-free and efficient Suzuki--Miyaura reaction of $N$-methyliminodiacetic acid boronates in water
Authors : Chun Liu, Xinmin Li, Xinnan Wang, Jieshan Qiu
Pages : 1208-1215
View : 6 | Download : 4
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :A green and efficient protocol has been developed for the Pd(OAc)$_{2}$-catalyzed ligand-free Suzuki--Miyaura reaction of $N$-methyliminodiacetic acid (MIDA) boronates in water. In the presence of Pd(OAc)$_{2}$ as a catalyst and ($i$-Pr)$_{2}$NH as a base, the cross-coupling reactions of aryl bromides with aryl MIDA boronates proceeded smoothly in water without any surfactant, and various functional groups were tolerated under the optimized conditions.Keywords : Palladium, ligand-free, Suzuki--Miyaura reaction, $N$-methyliminodiacetic acid boronates, water