- Turkish Journal of Chemistry
- Vol: 38 Issue: 4
- Application of 3-aroyl-4(5)-arylimidazols as efficient ligands in Pd-catalyzed Heck reactions
Application of 3-aroyl-4(5)-arylimidazols as efficient ligands in Pd-catalyzed Heck reactions
Authors : Mojtaba Amini, Seyedeh Motahhareh Amini, Bagher Eftekhari-sis, Ali Keivanloo
Pages : 547-552
Doi:10.3906/kim-1307-18
View : 13 | Download : 4
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :The Heck coupling of haloarenes with various alkenes was successfully performed in the presence of 0.25 mol % PdCl2 and 0.5 mol % biphenyl-4-yl-[4(5)-(biphenyl-4-yl)-1H-imidazol-2-yl]ketone 2f as a ligand with Na2CO3 as optimal base, in a 1:1 mixture of H2O/DMF as the reaction solvent at 80 °C for 8 h. Imidazole 2f was found to be an inexpensive, air-stable, easily available, and efficient ligand in the palladium-catalyzed Heck reactions of aryl iodides (76 %--94 %), bromides (52 %--79 %), and chlorides (40 %--70 %).Keywords : Aroylimidazoles, PdCl2, Heck reaction, aqueous medium