- Turkish Journal of Chemistry
- Vol: 27 Issue: 1
- An Efficient Synthesis of Alnustone, a Naturally Occurring Compound
An Efficient Synthesis of Alnustone, a Naturally Occurring Compound
Authors : Süleyman Göksu, Hülya Çelik, Hasan Seçen
Pages : 31-34
View : 9 | Download : 4
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :Alnustone, 4(E),6(E)-1,7-diphenyl-hepta-4,6-dien-3-one, was synthesized starting from benzaldehyde in three steps with an overall yield of 57%. The condensation of benzaldehyde with acetone gave benzalacetone. The Pd-C catalyzed hydrogenation of benzalacetone afforded benzylacetone. The in situ enamination of benzylacetone with pyrrolidine and acetic acid followed by cinnamaldehyde treatment gave alnustone.Keywords : alnustone, 4(E), 6(E)-1, 7-diphenyl-hepta-4, 6-dien-3-one, diarylheptanoid, benzaldehyde, benzalacetone, benzylacetone, cinnamaldehyde