- Turkish Journal of Chemistry
- Vol: 28 Issue: 2
- Iridoid and Phenylethanoid Glycosides from Verbascum lasianthum
Iridoid and Phenylethanoid Glycosides from Verbascum lasianthum
Authors : Zeliha Ş. Akdemir, I. Irem Tatli
Pages : 227-234
View : 19 | Download : 5
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :Three iridoid glucosides, 8-O-acethylharpagide (1), harpagoside (2), and 6-O-vanilloylajugol (3), were isolated from the roots of Verbascum lasianthum Boiss. ex Bentham. In addition, 2 phenylethanoid glycosides, verbascoside {=acteoside, [b -(3,4-dihydroxyphenyl)-ethyl]-(3' -O-a -L-rhamnopyranosyl)-(4' -O-caffeoyl)-b -D-glucopyranoside} (4) and poliumoside {= [b -(3,4-dihydroxyphenyl)-ethyl]-(3',6' -O-a -L-dirhamnopyranosyl)-(4' -O-caffeoyl)-b -D-glucopyranoside} (5), were also isolated. The structures of all compounds were established by spectroscopic evidence (UV, IR, 1D and 2D NMR, LC-ESIMS). Compounds 2-5 demonstrated scavenging properties toward the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical in TLC autographic assays.Keywords : Verbascum lasianthum, Scrophulariaceae, iridoid glucosides, 8-O-acethylharpagide, harpagoside, 6-O-vanilloylajugol, phenylethanoid glycosides, verbascoside (= acteoside), poliumoside, radical scavenging activity