- Turkish Journal of Chemistry
- Vol: 28 Issue: 2
- Synthesis and Some Reactions of 4-Benzoyl-5-Phenyl-1-(2,4,6-Trichloro Phenyl)-1H-Pyrazole-3-Carboxyl...
Synthesis and Some Reactions of 4-Benzoyl-5-Phenyl-1-(2,4,6-Trichloro Phenyl)-1H-Pyrazole-3-Carboxylic Acid
Authors : Ahmet Şener, Ishak Bildirici
Pages : 149-156
View : 10 | Download : 5
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :Furandione 1 was reacted with 2,4,6-trichlorophenylhydrazine to give the 1H-pyrazole-3-carboxylic acid 2 together with a new pyridazinone derivative 3. Then 2 was converted into the corresponding ester 5 or amide 6 derivatives, respectively, via reactions of its acid chloride 4 with various alcohols or N-nucleophiles. Nitrile derivative 7 was obtained by dehydration of 6a in a mixture of SOCl2 and DMF. Condensation reactions of 2 with some hydrazines led to the formation of pyrazolo [3,4-d] pyridazinone 8 derivatives.Keywords : Cyclic oxalyl compounds, Pyrazole, Pyridazine, Pyrazolo [3, 4-d] Pyridazinone