- Turkish Journal of Chemistry
- Vol: 28 Issue: 5
- Studies on the Reactions of 4-Ethoxycarbonyl-5-phenyl-2,3-dihydro-2,3- furandione with Some NH Nucle...
Studies on the Reactions of 4-Ethoxycarbonyl-5-phenyl-2,3-dihydro-2,3- furandione with Some NH Nucleophiles
Authors : Ahmet Şener, Hasan Genç, Israfil Tozlu, M. Kasım Şener
Pages : 659-666
View : 11 | Download : 2
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :4-Ethoxycarbonyl-5-phenyl-2,3-dihydro-2,3-furandione 1 was reacted with o-phenylenediamine, substituted ureas and methylcarbamate or acetamide to give quinoxaline 2, pyrimidine 3 and benzoylmalonic acid 4 derivatives, respectively. Benzoylmalonic acid derivative 4a was converted into a new oxozinedione derivative, 5, by refluxing its solution in xylene containing a catalytic amount of p-toluene sulfonic acid. In addition, triphenylpyrazole carboxylic acid derivative 6 was obtained from the reaction of 4a with diphenylhydrazine.Keywords : Cyclic oxalyl compounds, quinoxaline, pyrimidine, benzoylmalonic acid, oxazine, pyrazole carboxylic acid.