- Turkish Journal of Chemistry
- Vol: 31 Issue: 6
- Fused Heterocycles: Synthesis of Some New Imidazopyridines as Anti-Mycobacterial Agents
Fused Heterocycles: Synthesis of Some New Imidazopyridines as Anti-Mycobacterial Agents
Authors : Birgül Özden Kasimoğullari, Zafer Cesur
Pages : 617-622
View : 10 | Download : 5
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :The reaction of semicarbazones bearing an imidazo[1,2-a]pyridine ring system with mercaptoacetic acid was investigated. The anti-mycobacterial activity of the compounds thus obtained were evaluated against Mycobacterium tuberculosis H37Rv, using rifampin as the standard. Only IVe showed activity at 6.25 m g mL-1.Keywords : Imidazo[1, 2-a]pyridine, semicarbazones, 4-thiazolidinone, antituberculous activity