- Turkish Journal of Chemistry
- Vol: 31 Issue: 6
- A Convenient and Efficient Synthesis of N-Acylsulfonamides in the Presence of Silica Phosphoric Acid...
A Convenient and Efficient Synthesis of N-Acylsulfonamides in the Presence of Silica Phosphoric Acid under Heterogeneous and Solvent-Free Conditions
Authors : Ahmad Reza Massah, Mina Dabagh, Maryam Afshar, Ahmad Reza Momeni
Pages : 611-616
View : 12 | Download : 4
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :Reaction of sulfonamides with carboxylic acid anhydrides and chlorides in the presence of silica phosphoric acid provided N-acyl sulfonamides in good to high yields. All reactions were performed under mild conditions in solvent-free and heterogeneous systems and the products were obtained in high purity after a simple work-up. Silica phosphoric acid could be reused for 3 times without visible loss of activity.Keywords : N-acylsulfonamide, solvent-free, silica phosphoric acid, heterogeneous condition, N-acylation