- Turkish Journal of Chemistry
- Vol: 32 Issue: 3
- Synthesis of Some New 4-oxo-4H-Chromene Derivatives Bearing Nitrogen Heterocyclic Systems as Antifun...
Synthesis of Some New 4-oxo-4H-Chromene Derivatives Bearing Nitrogen Heterocyclic Systems as Antifungal Agents
Authors : Tarik El-sayed Ali, Salah Abdel-aghfaar Abdel-aziz
Pages : 365-374
View : 9 | Download : 6
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :Some new 4-oxo-4H-chromone derivatives bearing nitrogen heterocyclic systems were achieved by treatment of 3-[(4-aminophenylimino) methyl]-6-chloro-4-oxo-4H-chromene (2) with some aldehydes, cyclic oxygen, and halogen compounds, followed by heterocyclization. Significant antifungal activities were observed for some of the prepared compounds. Structures of all products were confirmed by elemental analysis, IR, 1H-NMR, and mass spectra.Keywords : Chromone, nitrogen heterocycles, antifungal activity