- Turkish Journal of Chemistry
- Vol: 33 Issue: 4
- A novel naphthoquinone glycoside from Rubia peregrina L.
A novel naphthoquinone glycoside from Rubia peregrina L.
Authors : Ufuk Özgen, Cavit Kazaz, Hasan Seçen, Ihsan Çaliş
Pages : 561-568
View : 16 | Download : 8
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :A phytochemical study was performed on the subterranean parts (roots and rhizomes) of Rubia peregrina. The substances were isolated from chloroform, ethyl acetate, and water soluble parts of the methanolic extract using several chromatographic techniques. 1-Hydroxy-2-methyl-9,10-anthraquinone (1), 1,3-dihydroxy-2-methyl- 9,10-anthraquinone (2), and 1,3-dihydroxy-2-methoxymethyl-9,10- anthraquinone (3) were isolated from the chloroform phase; and asperuloside (4), asperulosidic acid (5), rubiadin 3-O-b-primeveroside (6), lucidin 3-O-b -primeveroside (7), deacetylasperulosidic acid (8), liriodendrin (9), and a new naphthoquinone glycoside, 2-hydroxy-3-O-b-primeveroside naphthalene-1,4-dione (inkumoside, 10), from the aqueous phase. The structures of the compounds were elucidated by means of spectral analysis (1H-NMR, 13C-NMR, 2D-NMR--COSY, HMBC, HMQC-, EI-MS and ESI-MS).Keywords : Rubia peregrina, Rubiaceae, anthraquinones, iridoid glycosides, naphthoquinone glycoside.