- Turkish Journal of Chemistry
- Vol: 33 Issue: 6
- An efficient one pot synthesis of 1,4-dihydropyridines using alumina sulfuric acid (ASA) catalyst
An efficient one pot synthesis of 1,4-dihydropyridines using alumina sulfuric acid (ASA) catalyst
Authors : Mustafa Arslan, Cüneyt Faydali, Mustafa Zengin
Pages : 769-774
View : 13 | Download : 5
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :An efficient synthetic method for 1,4-dihydropyridines has been developed using 3 or 4 component condensation reactions of aldehydes, 1,3-dicarbonyl compounds, and ammonium acetate in the presence of alumina sulfuric acid catalyst in minimum methanol at reflux temperature. This procedure offers several advantages including high yields, an environmentally friendly procedure, short reaction times, and a simple work-up procedure.Keywords : Hantzsch, 1, 4-dihydropyridines, ASA catalyst, one pot conversion.