- Turkish Journal of Chemistry
- Vol: 36 Issue: 2
- Synthesis, characterization, and microwave-promoted catalytic activity of novel benzimidazole salts ...
Synthesis, characterization, and microwave-promoted catalytic activity of novel benzimidazole salts bearing silicon-containing substituents in Heck-Mizoroki and Suzuki-Miyaura cross-coupling reactions under aerobic conditions
Authors : Hasan Küçükbay, Nihat Şireci, Ülkü Yilmaz, Selma Deniz, Mehmet Akkurt
Pages : 201-217
Doi:10.3906/vet-1301-63
View : 11 | Download : 5
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :A number of benzimidazole derivatives (1-8) were synthesized and the catalytic activity of these compounds in a catalytic system including Pd(OAc)2 and K2CO3 in DMF-H2O was evaluated in Heck-Mizoroki and Suzuki-Miyaura cross-coupling reactions of aryl iodides, bromides, and chlorides with styrene and arylboronic acids under microwave irradiation and aerobic conditions. The yields of both the Heck-Mizoroki and the Suzuki-Miyaura cross coupling reactions with aryl iodides and aryl bromides were nearly quantitative. The synthesized 1-substituted benzimidazole (1) and benzimidazole salts (2-8) were identified by 1H- and 13C-NMR and IR spectroscopic methods, and micro analysis. The molecular structure of 7 was also determined by X-ray crystallography.Keywords : Benzimidazole salt, N-heterocyclic carbene, palladium catalysis, Heck-Mizoroki coupling reaction, Suzuki-Miyaura coupling reaction, microwave, crystal structure analysis