- Turkish Journal of Chemistry
- Vol: 36 Issue: 3
- Synthesis, characterization, and antioxidant activities of new trisubstituted triazoles
Synthesis, characterization, and antioxidant activities of new trisubstituted triazoles
Authors : Kemal Sancak, Yasemin Ünver, Dilek Ünlüer, Esra Düğdü, Gülcan Kör
Pages : 457-466
Doi:10.3906/vet-1302-34
View : 15 | Download : 7
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :A series of new 4-(3,4dimethoxyphenethyl)-3,5-akyl/aryl-4H- 1,2,4-triazoles (3a-g) were obtained by reaction of ethyl N'-(alkylidene/arylidene)hydrazonate (1) and 2-(3,4-dimethoxy phenyl)ethanamine (2). Compounds 4d, e, and g were synthesized from the reaction of corresponding compounds 3d, e, and g with BBr3, respectively. The 10 new compounds synthesized were characterized by elemental analyses, IR, 1H-NMR, and 13C-NMR spectral data. The structure of compound 3g was inferred through IR, 1H-, 13C-NMR, elemental analyses, and X-ray spectral techniques. In addition, the newly synthesized chemicals were screened for their antioxidant properties. Among the chemicals tested, 4d, e, and g exhibited the highest degree of antioxidant activity.Keywords : Synthesis, 1, 2, 4-triazole, antioxidant activity, boron tribromide, X-ray