- Turkish Journal of Chemistry
- Vol: 36 Issue: 5
- Synthesis and antimicrobial activity of some novel 4-hydroxyquinolin-2(1H)-ones and pyrano[3,2-c] qu...
Synthesis and antimicrobial activity of some novel 4-hydroxyquinolin-2(1H)-ones and pyrano[3,2-c] quinolinones from 3-(1-ethy1-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)-3-oxopropanoic acid
Authors : Hany Mohamed Hassanin, Magdy Ahmed Ibrahim
Pages : 682-699
Doi:10.3906/tar-1301-112
View : 11 | Download : 4
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :Chlorination, bromination, and condensation reactions of 3-(1-ethy1-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)-3-oxopropanoic acid (3) were studied. Some novel 4-hydroxyquinolin-2(1H)-ones and pyrano[3,2-c]quinolin-2(1H)-ones were also prepared. The structures of the novel compounds were established by elemental analyses and spectral data. All the products were also screened in vitro for their antimicrobial activity.Keywords : b-Ketoacid, 4-hydroxyquinolin-2(1H)-one, pyrano[3, 2-c]quinolinone, condensation reactions