- Turkish Journal of Chemistry
- Vol: 37 Issue: 1
- Synthesis, characterization, and antimicrobial activity of some new phosphorus macrocyclic compounds...
Synthesis, characterization, and antimicrobial activity of some new phosphorus macrocyclic compounds containing pyrazole rings
Authors : Tarik El-sayed Ali, Salah Abdel-aziz Abdel-ghaffar, Kamilia Mohamed El-mahdy, Somaia Mohamed Abdel-karim
Pages : 160-169
Doi:10.3906/kim-1205-18
View : 8 | Download : 3
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :A simple synthetic method is reported for the preparation of some new phosphorus macrocycles in which the pyrazole rings are appended to a phosphorus atom. The methodology is based on the cyclocondensation reaction of bis(4-formylpyrazolyl) phosphine oxide(1a, 1b) with nitrogen nucleophiles that contain active terminal amino groups. The antimicrobial activities of the synthesized compounds were assayed.Keywords : Key words: Phosphorus macrocycles, pyrazole, cyclocondensation, nitrogen nucleophiles