- Turkish Journal of Chemistry
- Vol: 37 Issue: 6
- Asymmetric Henry reaction catalyzed by Cu(I)-based chiral amino alcohol complex
Asymmetric Henry reaction catalyzed by Cu(I)-based chiral amino alcohol complex
Authors : Tianhua Shen, Quan Qin, Hang Ni, Ting Xia, Xiaocong Zhou, Funa Cui, Junqi Li, Deqiang Ran, Qingbao Song
Pages : 966-977
Doi:10.3906/kim-1210-62
View : 11 | Download : 4
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :The Cu(I)-based complex prepared from (S)-2-(furan-2-yl-methylamino)-2-phenylethanol (5c) and CuCl was used as catalyst in enantioselective Henry reactions of arylaldehydes and nitromethane, which gave 89% ee and 95% yield at ambient temperature. The proposed catalytic cycle of an asymmetric Henry reaction was suggested.Keywords : Chiral amino alcohol, copper(I) salt, asymmetric catalysis, Henry reaction