- Turkish Journal of Biology
- Vol: 24 Issue: 1
- Detection of Mutagenic Effects of 2, 4, 5 Tri (Sübstitüe) Phenyl Imidazole and Its Derivatives in Am...
Detection of Mutagenic Effects of 2, 4, 5 Tri (Sübstitüe) Phenyl Imidazole and Its Derivatives in Ames/Salmonella/Test System
Authors : Ayse Mercangöz
Pages : 57-64
View : 10 | Download : 5
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :The mutagenic effects of 2, 4, 5 tri-phenylimidazole and its nine different derivatives, which are aimed at producing medicine as a primary substance, were investigated by the Ames Salmonella/Microsome plate assay. The test compounds were directly effective, especially in the TA 98 strain. A relationship was found between the mutagenic effect and the positions of the methyl and methoxy groups.Keywords : Imidazole, 2, 4, 5 triphenyl imidazole, mutagenic activity, Ames/Salmonella/Microsome.