- Turkish Journal of Biology
- Vol: 32 Issue: 1
- Antipyretic Activity of Peperomia pellucida Leaves in Rabbit
Antipyretic Activity of Peperomia pellucida Leaves in Rabbit
Authors : Alam Khan, Moizur Rahman, Shariful Islam
Pages : 37-41
View : 8 | Download : 4
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :Antipyretic effects of petroleum ether and ethyl acetate soluble fractions of ethanol extract of the leaves of Peperomia pellucida (Linn.) HBK (Fam. Piperaceae) were investigated. Intraperitoneal administration of boiled milk at a dose of 0.5 ml/kg body weight in albino rabbit leads to pyrexia. Intraperitoneal (i.p.) administration of petroleum ether and ethyl acetate soluble fractions of ethanol extract of the leaves of P. pellucida at a dose of 80 mg/kg body weight significantly reduced the elevated body temperature of rabbit. This antipyretic effect has been compared with antipyretic effect of standard aspirin and the solvent used.Keywords : Peperomia pellucida, leaves, antipyretic, rabbits, boiled milk, aspirin