- Turkish Journal of Biology
- Vol: 35 Issue: 6
- Anti-inflammatory activity of Anthemis aciphylla var. aciphylla Boiss.
Anti-inflammatory activity of Anthemis aciphylla var. aciphylla Boiss.
Authors : Sinem Baltaci, Hatice Efsun Kolatan, Osman Yilmaz, Bijen Kivçak
Pages : 757-762
View : 19 | Download : 5
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :Ethanolic (EEAA) and sesquiterpene lactone (SEAA) extracts of the aerial parts of Anthemis aciphylla var. aciphylla Boiss. (Asteraceae) were evaluated for anti-inflammatory activity on carrageenin-induced paw edema (acute model) and cotton pellet-induced granuloma (chronic model) in rats. In carrageenin-induced paw edema, EEAA and SEAA at intraperitoneal doses of 50, 100, and 200 mg/kg dose-dependently inhibited the paw edema. In cotton pellet-induced granuloma, the oral administration of EEAA and SEAA at 50, 100, and 200 mg/kg dosages was also found to significantly inhibit granuloma tissue formation.Keywords : Key words: Anthemis aciphylla, anti-inflammatory activity, carrageenin, paw edema, cotton pellet