- Turkish Journal of Biology
- Vol: 35 Issue: 6
- Bioassay studies of 2'-O-ethylmurrangatin isolated from a medicinal plant, Murraya paniculata
Bioassay studies of 2'-O-ethylmurrangatin isolated from a medicinal plant, Murraya paniculata
Authors : Azizuddin Shaikh, Muhammad Iqbal Choudhary
Pages : 751-755
View : 9 | Download : 3
Publication Date : 9999-12-31
Article Type : Makaleler
Abstract :A secondary metabolite, 2'-O-ethylmurrangatin (1), was isolated from the leaves of a medicinal plant, Murraya paniculata. The structure of compound 1 was identified with the help of spectroscopic techniques. Compound 1 was screened for its antioxidant, lipoxygenase, prolyl endopeptidase, and respiratory burst inhibitory activities. 2'-O-Ethylmurrangatin (1) was found to have significant activity against lipoxygenase enzyme and moderate respiratory burst inhibitory activity, but no activity against either DPPH radical scavenging assay or prolyl endopeptidase enzyme.Keywords : Key words: Murraya paniculata, Rutaceae, 2'-O-ethylmurrangatin, antioxidant, DPPH radical scavenging assay, lipoxygenase inhibition assay, prolyl endopeptidase inhibition assay, respiratory burst inhibitory assay