THE SYNCHRONIZATION BEHAVIOR OF BASAL GANGLIA
Authors : Yüksel Çakir
Pages : 38-45
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Publication Date : 2019-12-31
Article Type : Research
Abstract :A network model of basal ganglia (BG) that comprises striatum, internal and external segments of globus pallidus, subthalamic nucleus, substantia nigra pars reticulate neuronal sub populations and thalamus is constructed. The dynamic behavior of network is investigated using Izhikevich neuron model. The influences of dopamine, the synaptic strength and the neuronal interconnection density on the synchronization behavior of the subpopulations are investigated. In the case of dopamine depletion, the increased striatal synchronization is observed. Considerable effect on the synchronization of other basal ganglia sub populations is not observed in the case of dopamine depletion. The highest synchronization values are observed for the lowest synaptic strength and the neuronal interconnection density. The decreased neuronal interconnection density causes a decrease in the fluctuation in synchronization in thalamic neurons depending on dopamine value.Keywords : basal ganglia, synchronization