- Koşuyolu Heart Journal
- Vol: 25 Issue: 1
- Prognostic Nutrition Index May Predict Cerebral Embolic Events Following Carotid Artery Stenting Pro...
Prognostic Nutrition Index May Predict Cerebral Embolic Events Following Carotid Artery Stenting Procedure
Authors : Ahmet Güner, Ömer Çelik, Ahmet Arif Yalçin, Murat Örten, Serkan Kahraman, Macit Kalçik, Ezgi Gültekin Güner, Çağdaş Topel, Mehmet Ertürk
Pages : 40-49
View : 24 | Download : 5
Publication Date : 2022-04-18
Article Type : Research
Abstract :Introduction: Cerebral embolism after carotid artery stenting (CAS) remains a matter of concern in frailty patients. The prognostic nutrition index (PNI), which provides an objective assessment of nutritional status, is a useful prognostic indicator in cardiovascular diseases. We aim to determine the value of pre-procedural PNI in predicting cerebral embolism including stroke, transient ischemic attack (TIA), and silent new ischemic cerebral lesions (SNICLs). Patients and Methods: We retrospectively evaluated 138 patients (mean age= 70.6 ± 6.7 years, male= 99) who underwent CAS. Inclusion criteria were as follows: i) availability of all medical records including albumin value and lymphocyte count, ii) having cranial imaging after CAS, iii) having symptomatic carotid stenosis 50-99% or asymptomatic carotid stenosis ≥60-99%. The study population was divided into two subgroups according to the presence of cerebral embolism as cerebral embolism (+) cerebral embolism (-) groups. Results: Among the study population, 22 patients (16%) had at least 1 SNICL, seven patients (5.0%) had an ischemic stroke, and five patients (3.6%) had TIA. The cerebral embolism (+) group had a significantly lower PNI, older age, more frequent history of stroke, a higher proportion of type III aortic arch, and longer fluoroscopy time than the cerebral embolism (-) group. Low PNI was identified as one of the independent predictors of cerebral embolism (OR= 0.808; 95% CI= 0.670-0.975; p= 0.026), and PNI lower than 44.7 predicted cerebral embolism with a sensitivity of 70.6% and a specificity of 61.1% (AUC= 0.739; 95% CI= 0.651 to 0.827; p< 0.001). Conclusion: The current data suggest that PNI is an independent prognostic factor for cerebral embolic complications after CAS procedures.Keywords : Stroke, magnetic resonance imaging, carotid artery, stent endovascular