- Journal of Experimental and Clinical Medicine
- Cilt: 40 Sayı: 3
- Retrospective evaluation of lateral ventricular volume in Parkinson\'s patients and control group on...
Retrospective evaluation of lateral ventricular volume in Parkinson\'s patients and control group on magnetic resonance images
Authors : Mert Nahir, Berna Doğan
Pages : 572-577
View : 150 | Download : 196
Publication Date : 2023-09-30
Article Type : Research
Abstract :Due to its flexible and expandable nature, the lateral ventricle volume has the potential to change in response to neurodegenerative diseases. Therefore, our study aims to calculate the lateral ventricle volume and its ratios to both the intracranial and cerebrum volumes and compare these measurements between Parkinson\'s patients and controls. By examining these ratios, we aim to better understand the relationship between lateral ventricle volume and brain structure in the context of Parkinson\'s disease. Magnetic resonance imaging of 54 Parkinson\'s patients (13 female; 41 male) and 26 healthy controls (8 female; 18 male) were included in the study. Lateral ventricle and intracranial volumes were calculated using the Cavalieri method in the ImageJ program on magnetic resonance images. Cerebrum volume was calculated using the BrainSuite program. It was observed that female patients with Parkinson\'s had a higher right-sided lateral ventricle volume than female controls. The right-sided lateral ventricle volume ratio to cerebrum volume and intracranial volume was also higher (p<0.05). Changes in ventricle volume are of great importance in diseases due to their relationship with anatomical structures. As seen in the results of our study, we think that the gender factor should be taken into account when evaluating the ventricle volume in neurodegenerative diseases.Keywords : BrainSuite, ImageJ, Horos, Cerebrum Volume, Intracranial Volume