- Journal of the Turkish Chemical Society Section A: Chemistry
- Vol: 8 Issue: 2
- Cefoperazone metal complexes and their antimicrobial investigations
Cefoperazone metal complexes and their antimicrobial investigations
Authors : Mehmet Emin ÇINAR, Taner ERDOĞAN, Ayşegül GÖLCÜ
Pages : 375-390
Doi:10.18596/jotcsa.721414
View : 13 | Download : 3
Publication Date : 2021-05-31
Article Type : Research
Abstract :Transition metal (Cd(II), Co(II), Cu(II), Fe(III), Ni(II), Pd(II), Pt(II), Ru(III), Zn(II)) complexes of cefoperazone (CFP) were synthesized and their spectroscopic (IR, UV-Vis), magnetic, thermal (DTA-TG) and mass investigations were conducted to characterize the metal-based complexes. Detailed insights into the electronic structures were provided by performing density functional theory (DFT) computations. Their antimicrobial studies were realized rendering their activities compared to that of the commercial cefoperazone.Keywords : Cefoperazone, metal complexes, antimicrobial studies, computation