- Journal of the Turkish Chemical Society Section A: Chemistry
- Vol: 5 Issue: 1
- An Effective Method to Synthesize 2,3-Dihydroquinazolin-4(1H)- One Using Phosphate Fertilizers (MAP,...
An Effective Method to Synthesize 2,3-Dihydroquinazolin-4(1H)- One Using Phosphate Fertilizers (MAP, DAP and TSP) as Green Heterogeneous Catalysts
Authors : Youssef Merroun, Soukaina Chehab, Touriya Ghailane, Said Boukhris, Rachida Ghailane, Nouzha Habbadi, Amina Hassikou, Brahim Lakhrissi, Abdelaziz Souizi
Pages : 303-316
Doi:10.18596/jotcsa.363818
View : 5 | Download : 2
Publication Date : 2017-09-01
Article Type : Research
Abstract :In this work, an efficient, easy, and green process has been developed for the synthesis of 2,3-dihydroquinazolin-4(1H)-one from a condensation reaction of anthranylamide with various aromatic aldehyde using of phosphate fertilizers, mono-ammonium phosphate (MAP), di-ammonium phosphate (DAP) and triple super phosphate (TSP) as heterogeneous catalysts. The reaction conditions were optimized taking into account of some parameters which control the reaction, namely the nature and the volume of the solvent and the mass of catalyst. The results show that the catalysts used herein are very interesting because they present a good catalytic activity and they are reusable for at least five cycles without any degradation of their activity .Keywords : Heterogeneous catalysis, fertilizer phosphate, MAP, DAP