- Journal of the Turkish Chemical Society Section A: Chemistry
- Vol: 4 Issue: 3
- Total Syntheses of Balsacone B and Balsacone C
Total Syntheses of Balsacone B and Balsacone C
Authors : Serdar Burmaoğlu
Pages : 709-720
Doi:10.18596/jotcsa.311736
View : 4 | Download : 2
Publication Date : 2017-06-13
Article Type : Research
Abstract :The first total syntheses of Balsacone C (16) and Balsacone B (17), mainly based on a convergent strategy, were described. The crucial step of this strategy was the alkylation of trihydroxydihydrochalcone derivatives 7 and 8 with cinnamylbromide derivative 13. For this, compounds 7 and 8 were prepared starting from trihydroxyacetophenone (1) in four steps. Then compound 13 was prepared starting from coumaric acid (9) in four steps.Keywords : Synthesis, natural product, Balsacone B, Balsacone C