- Journal of the Turkish Chemical Society Section A: Chemistry
- Vol: 4 Issue: 2
- CSA-Catalyzed Three-component Synthesis of Fused Polycyclic Pyrazolo[4,3-e]pyridines Under Ultrasoni...
CSA-Catalyzed Three-component Synthesis of Fused Polycyclic Pyrazolo[4,3-e]pyridines Under Ultrasonic Irradiation and Their Antioxidant Activity
Authors : Emel Pelit
Pages : 631-648
Doi:10.18596/jotcsa.295465
View : 11 | Download : 7
Publication Date : 2017-03-14
Article Type : Research
Abstract :New fused pyrazolo[4,3-e]pyridines were obtained by multi-component reaction of 1,3-dimethyl-1 H -pyrazol-5-amine or 3-phenyl-1 H -pyrazol-5-amine, aromatic aldehydes and indan-1,3-dione in the presence of camphor-10-sulfonic acid (CSA) as an effective catalyst under ultrasound promoted conditions. The antioxidant activity of the pyrazolopyridine compounds 4b , 5c , 5e , 7a , 7b and 7c were determined.Keywords : Pyrazolopyridines, multi-component synthesis, ultrasonic irradiation, camphor-10-sulfonic acid (CSA)