- Journal of Immunology and Clinical Microbiology
- Vol: 7 Issue: 1
- Evaluation Of Antimicrobial Activities Of Extract From Johrenıa Paucijuga (D.C.) Bornm
Evaluation Of Antimicrobial Activities Of Extract From Johrenıa Paucijuga (D.C.) Bornm
Authors : Husniya MAMMADOVA, Ema AGAYEVA, Vidadi NARİMANOV
Pages : 1-4
View : 6 | Download : 4
Publication Date : 2022-03-29
Article Type : Research
Abstract :Background: J.paucijuga (D.C.) Bornm is known to grow in Azerbaijan. Our investigation has revealed a new distribution area situated in the Gadabay region –Middle Mountain Beltgrasslands of Small Caucasus. The purpose of the study was to evaluate antimicrobial activities of extracts from J.pucijuga (D.C.) Bornm. Materials and Methods: The plant was collected in July 2017 and further investigated for chemical composition. Results of scientific trips have revealed the expansion of the distribution range of some plants and the reduction of other members of the Apiaceae family. Investigations related to the selection of medicinal plants, identification of their biological features, investigation of species ontogenesis, distribution range, chemical composition, evaluation of biological and exploitation reserves are always of importance. Chemical compounds characteristic of this plant - β-sitosterol and β-stigmasterol were detected in our previous research. Extract obtained from J.paucijuga (D.C.) Bornm was tested for antimicrobial activity using the disk diffusion method as a part of the cooperation between the Department of Plant Resources of İnstitute of Botany of Azerbaijan National Sciences Academy and the Department of Medical Microbiology. Results: Thus, the study of bactericide and fungicide activity of J.pucijuga extract has shown that the aqueous extract of this plant (1:10) has antimicrobial and antifungal activity against experimental strains depending on the concentration of the extract of the plant and exposure time. J.paucijuga essential oils have shown comparatively higher bactericide activity. Conclusions: The purpose of the study was to evaluate antimicrobial activities of extracts from J.pucijuga (D.C.) Bornm to use it in the prophylaxis of bacterial diseases as preparation antimicrobial hygienic solutions, antibacterial and antifungal ointment. The obtained formula 2 proves that the structural formula of coumarin is the same as the structure formula we are identified [8].Keywords : Johrenia paucijuga (D.C.) Bornm, Apiaceae Lindl, antimicrobial, antifungal, β-stigmasterol