- Journal of Health Sciences and Medicine
- Vol: 6 Issue: 2
- Immature granulocyte and other markers in prediction of mortality in spontaneous intracerebral hemor...
Immature granulocyte and other markers in prediction of mortality in spontaneous intracerebral hemorrhage
Authors : Idris Kocatürk, Sedat Gülten
Pages : 368-373
Doi:10.32322/jhsm.1225428
View : 7 | Download : 3
Publication Date : 2023-03-27
Article Type : Research
Abstract :Aim: This study aims to evaluate immature granulocyte count (IG#) and percentage (IG%) in the prediction of mortality in spontaneous intracerebral hemorrhage (SICH). Material and Method: Demographic characteristics and laboratory test results of patients diagnosed with SICH and admitted to the neurology clinic in a tertiary hospital between January 1, 2020, and January 1, 2022, were recorded. One hundred ten patients were included in the study. While 80 of these patients constituted the group that recovered after treatment, 30 of them formed the group that died despite treatment. IG and other laboratory and clinic parameters were statistically compared in both groups. Results: Of 110 patients, 45 (42.7%) were female, and 65 (57.3%) were male. IG counts were higher in the non-survival group than in the survival group (p=0.001). When the patients were divided according to low IG% ( =0.6), 30 patients were in the high IG# group, and 80 patients were in the low IG% group. White blood cell (WBC), neutrophil count (NEUT#), monocyte count (MONO#), IG#, neutrophil-lymphocyte ratio (NLR), and hemorrhage volume (HV) values were statistically significantly higher in the high IG% group than in the low IG% group; Glasgow coma score (GCS) and percentage of lymphocytes (LYMPH%) values were significantly lower too. In addition, the mortality rate in the high IG# group was significantly higher than the mortality rate in the low IG% group (53.23% vs. 17.5%). Conclusion: IG is a new, easily accessible, inexpensive, and promising marker for predicting in-hospital mortality in patients with SICH.Keywords : Spontaneous intracerebral hemorrhage, inflammation, immature granulocyte, prognosis, mortality