- Journal of Contemporary Medicine
- Cilt: 13 Sayı: 6
- \"Relationship between Increased Epicardial Fat Tissue and Aortic Dilatation: may be an Indicat...
\"Relationship between Increased Epicardial Fat Tissue and Aortic Dilatation: may be an Indicator of Hypertension Complications\"
Authors : Nurullah Yücel, Tayfun Aygun, Meryem Esma Düz, Gulam Hekimoğlu, Mustafa Ahmet Huyut, Mehmet Kizilay, Muzaffer Şeker
Pages : 1109-1116
View : 54 | Download : 74
Publication Date : 2023-11-30
Article Type : Research
Abstract :Abstract Background/Aims: Epicardial fat tissue (EFT) refers to the adipose tissue on the myocardium\'s surface and beneath the visceral pericardium. It participates in the endocrine system as well as the myocardium\'s energy metabolism. This study aimed to investigate the potential of EFT as a noninvasive marker for hypertension (HT) complications associated with aortic dilatation. Methods: The study\'s healthy control (HC) group consisted of 70 patients with normal blood pressure and the HT group consisted of 82 patients with higher blood pressure. HT groups were separated into four categories, prehypertensive, stage 1, stage 2, and stage 3. EFT was assessed by two-dimensional echocardiography from the parasternal long axis and compared between the HC and the HT groups. Results: The EFT thickness in the HT group was considerably higher than in the HC (5.7±1.9 vs 4.0±1.3, p<0.05). In multivariate regression analysis, office blood pressure (p<0.05, 95% CI 0.827-0.935), ejection fraction (p<0.05, 95% CI 1.033-1.495), and EFT (p<0.05, 95% CI 0.413-0.807) were found to be independent variables in the separation of HT and HC groups. EFT thickness had a sensitivity of 73.2 and a specificity of 57.1% at a cut-off value of 4.15. EFT was significantly correlated with sinus valsalva (r2=0.08, p<0.05), sinotubular junction (r2=0.06, p<0.05), and aorta ascendence diameter (r2=0.07, p<0.05), respectively. EFT among HT subgroups, no differences were identified. Conclusion: EFT can be a marker revealing an increased risk of HT-related complications.Keywords : hipertansiyon, morfometri, biyobelirteç, epikardiyal yağ dokusu, komplikasyonlar