- Journal of Contemporary Medicine
- Cilt: 13 Sayı: 5
- The Evaluation of Testes by Shear Wave Elastography in Patients with Isolated Hypogonadotropic Hypog...
The Evaluation of Testes by Shear Wave Elastography in Patients with Isolated Hypogonadotropic Hypogonadism
Authors : Osman Dere, Hüseyin Karaaslan
Pages : 729-734
Doi:10.16899/jcm.1330250
View : 54 | Download : 34
Publication Date : 2023-09-30
Article Type : Research
Abstract :Aim: The aim of this study was to evaluate testicular stiffness by shear wave elastography (SWE) in patients with isolated hypogonadotropic hypogonadism (IHH) and to compare it with healthy controls. Methods: In this prospective study, 35 patients with IHH (group 1) and 40 healthy controls (group 2) were evaluated. These two groups were compared in terms of age, testicular volume, and SWE values. In a subsequent analysis, IHH patients were divided into 3 groups: those who were newly diagnosed and did not receive any treatment (group A), those who received testosterone replacement (group B), and those who received human chorionic gonadotrophin alpha (hCG) (group C). Testicular volumes and SWE values were also compared between these subgroups. Results: Testicular volumes were significantly lower in group 1 than in group 2 (p<.001). Group 1 had significantly higher testicular SWE values than group 2 (p<.001). There was also a negative correlation between the mean value of testicular stiffness and testicular volume in group 1 (r=-0.555, p=.001 for right testes, r=-0.403, p=.016 for left testes). Results of subsequent analysis by treatment status showed that patients in group C had significantly increased testicular volumes. In addition, they tended to have lower SWE values, when compared to groups A and B. Conclusions: SWE values were significantly higher in IHH patients compared to healthy controls. We found significant improvements in SWE values even in patients receiving short-term hCG replacement. Further research is needed on whether basal SWE values of IHH patients can predict fertility in patients with IHH.Keywords : izole hipogonadotropik hipogonadizm, elastografi, testiküler sertlik, erkek infertilitesi